Dudley K Strickland Selected Research

Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)

1/2021	Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.
7/2015	Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain.
1/2015	Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
3/2013	Engulfment adaptor phosphotyrosine-binding-domain-containing 1 (GULP1) is a nucleocytoplasmic shuttling protein and is transactivationally active together with low-density lipoprotein receptor-related protein 1 (LRP1).

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Dudley K Strickland Research Topics

Disease

9	Inflammation (Inflammations) 11/2022 - 09/2009
8	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 07/2002
5	Aneurysm (Aneurysms) 01/2023 - 09/2013
4	Atherosclerosis 12/2016 - 11/2003
3	Hemophilia A (Haemophilia) 10/2022 - 03/2014
3	Fibrosis (Cirrhosis) 01/2019 - 09/2013
3	Ischemic Stroke 10/2017 - 10/2007
3	Amyloid Plaque 05/2005 - 07/2002
2	Vascular System Injuries 01/2023 - 01/2021
2	Vascular Remodeling 01/2023 - 01/2011
2	Hemorrhage 10/2022 - 12/2016
2	Aortic Aneurysm (Aneurysm, Aortic) 01/2021 - 01/2018
2	Peritonitis 11/2019 - 11/2016
2	Stroke (Strokes) 10/2017 - 10/2007
2	Neoplasms (Cancer) 12/2016 - 05/2004
2	Osteoarthritis 03/2014 - 02/2013
2	Ischemia 07/2011 - 07/2008
2	Neuroblastoma 03/2010 - 09/2008
2	Brain Ischemia (Cerebral Ischemia) 12/2009 - 11/2003
1	Neointima 01/2023
1	Thoracic Aortic Aneurysm 01/2021
1	Tauopathies 01/2021
1	Myocarditis (Carditis) 01/2019
1	Body Weight (Weight, Body) 01/2018
1	Insulin Resistance 01/2018
1	Brain Neoplasms (Brain Tumor) 12/2017
1	Cerebral Hemorrhage 10/2017
1	Arthritis (Polyarthritis) 12/2016
1	Myocardial Ischemia (Ischemic Heart Diseases) 11/2016
1	Reperfusion Injury 11/2016
1	Connective Tissue Diseases (Connective Tissue Disease) 10/2016
1	Hyperplasia 10/2015
1	Pathologic Processes 07/2015
1	Ascending Aorta Aneurysm 01/2015
1	Rupture 01/2015
1	Abdominal Aortic Aneurysm 01/2015
1	Chondrosarcoma 01/2013
1	Myocardial Infarction 07/2011
1	Hypoxia (Hypoxemia) 07/2011

Drug/Important Bio-Agent (IBA)

8	LDL Receptors (LDL Receptor)IBA 01/2018 - 07/2002
5	Proteins (Proteins, Gene)FDA Link 11/2018 - 07/2002
5	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2017 - 11/2003
4	FibrinIBA 11/2022 - 01/2012
4	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 01/2021 - 03/2013
3	Amyloid (Amyloid Fibrils)IBA 04/2024 - 01/2004
3	VLDL receptorIBA 11/2022 - 05/2004
3	LigandsIBA 01/2021 - 07/2002
3	Peptides (Polypeptides)IBA 11/2019 - 05/2004
3	Lipoproteins (Lipoprotein)IBA 01/2015 - 10/2003
3	Amyloid beta-PeptidesIBA 03/2010 - 05/2005
3	Apolipoproteins E (ApoE)IBA 09/2009 - 07/2002
2	src-Family KinasesIBA 11/2022 - 11/2019
2	Factor VIII (Coagulation Factor VIII)IBA 10/2022 - 12/2016
2	AminopropionitrileIBA 01/2021 - 01/2018
2	EnzymesIBA 11/2019 - 03/2014
2	Platelet-Derived Growth FactorIBA 10/2017 - 09/2013
2	platelet-derived growth factor C (PDGF-C)IBA 10/2017 - 07/2008
2	Metalloproteases (Metalloproteinases)IBA 10/2016 - 03/2014
2	Aggrecans (Aggrecan)IBA 03/2014 - 02/2013
2	PlasminogenIBA 02/2009 - 11/2003
1	sortilinIBA 04/2024
1	Antisense OligonucleotidesIBA 01/2023
1	Losartan (Cozaar)FDA LinkGeneric 01/2023
1	AngiotensinogenIBA 01/2023
1	Fibrinogen (Factor I)FDA Link 11/2022
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 11/2022
1	estropipate (Ogen)FDA LinkGeneric 11/2022
1	1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA 01/2021
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2021
1	ImmunosorbentsIBA 11/2019
1	cadherin 5IBA 11/2019
1	Fibrin Fibrinogen Degradation ProductsIBA 11/2019
1	CytokinesIBA 01/2019
1	MidkineIBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	Silicone Elastomers (SE 30)IBA 01/2018
1	DNA Transposable Elements (Element, IS)IBA 12/2017
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 10/2017
1	Matrix Metalloproteinase 13IBA 12/2016
1	Monoclonal AntibodiesIBA 11/2016
1	VLDL LipoproteinsIBA 11/2016
1	NDSK-IIIBA 11/2016
1	Monomeric GTP-Binding ProteinsIBA 10/2015
1	Alanine (L-Alanine)FDA Link 10/2015
1	Myristoylated Alanine-Rich C Kinase SubstrateIBA 10/2015
1	Protein Kinases (Protein Kinase)IBA 10/2015
1	Angiotensin IIIBA 01/2015
1	ThrombospondinsIBA 03/2014
1	DisintegrinsIBA 03/2014
1	Proteoglycans (Proteoglycan)IBA 03/2014
1	Blood Proteins (Serum Proteins)IBA 03/2014
1	von Willebrand FactorIBA 03/2014
1	Connective Tissue Growth FactorIBA 09/2013
1	Tissue Inhibitor of Metalloproteinase-3IBA 01/2013
1	IntegrinsIBA 09/2011
1	LipidsIBA 07/2011
1	ElementsIBA 07/2011

Therapy/Procedure

2	Therapeutics 11/2016 - 03/2010
1	Thrombolytic Therapy 10/2017
1	Ligation 10/2015